WebINCB13739 is an orally effective, selective and tissue-specific 11β-HSD1 (11β-hydroxysteroid dehydrogenase 1) inhibitor with IC50 values of 3.2 nM (11β-HSD1 enzyme) and 1.1 nM (11β-HSD1 PBMC), respectively.INCB13739 can be used in type 2 diabetes mellitus (T2DM) and obesity studies. Chemical Information WebJan 1, 2008 · In a phase IIb clinical trial in type 2 diabetic patients, INCB13739 produced lowering of hemoglobin A1c , fasting plasma glucose, and HOMA-IR as well as a modest …
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WebJun 7, 2006 · WILMINGTON, Del.--(BUSINESS WIRE)--June 7, 2006--Incyte Corporation (Nasdaq:INCY - News) today announced that it has initiated a Phase I clinical trial of INCB13739, an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be … WebJun 6, 2009 · Results Presented at the ADA 69th Scientific Sessions Demonstrate that INCB13739, Incyte’s Oral 11beta-HSD1 Inhibitor, Significantly Improves Glycemic Control, … mudvayne scream with me you tube
Material Safety Data Sheet of INCB13739 AbMole BioScience
Webincb013739 incb13739 incb 13739 incb-13739 Organizations (1) Research & Development (1) Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort; Marketing (0) Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort ... WebIn a randomized, placebo-controlled Phase II study of overweight or obese patients with T2DM exhibiting inadequate glycemic control with metformin, an 11β-HSD1 inhibitor, INCB13739 (Incyte, Wilmington, DE, USA), significantly reduced A 1C and FPG compared with placebo. 122 Body weight, insulin resistance, and total cholesterol levels were also ... WebINCB13739 : Catalog Number: M21098: CAS Number: 869974-19-6: 1.2 Relevant identified uses of the substance or mixture and uses advised against; Identified uses: For research use only, not for human or veterinary use. 1.3 Details of the supplier of the safety data sheet; Company: Abmole Bioscience Inc. 8300 Cypress Creek Parkway, Suite 450 ... mudvayne new album 2022