Cub and sushi multiple domains 1
WebApr 10, 2024 · Autism spectrum disorder (ASD) is a neurodevelopmental disorder with highly heritable heterogeneity. Mutations of CUB and sushi multiple domains 3 ( CSMD3) gene have been reported in individuals with ASD. However, the underlying mechanisms of CSMD3 for the onset of ASD remain unexplored.
Cub and sushi multiple domains 1
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WebDec 12, 2024 · Although the genetic alteration of CUB and Sushi multiple domains 1 (CSMD1) is known to be associated with poor prognosis in several cancers, there is a lack of clinical relevance in head and neck cancer. WebJan 1, 2024 · CUB and sushi domains protein 1 Physicochemical Properties CSMD1 is synthesised as a single-chain precursor of 3565 amino acids including a 26 amino acid leader peptide. 1 Structure CSMD1 is composed of 14 CUB domains and 28 complement control protein domains (CCP; a.k.a., sushi domains).
WebAug 20, 2013 · Human CUB and Sushi multiple domains 1 (CSMD1) is a transmembrane (TM) protein of unknown function. It is composed of 14 CUB domains at the N terminus separated from each other by 14 CCP … WebCsmd1 CUB and Sushi multiple domains 1 [ (house mouse)] Gene ID: 94109, updated on 26-Sep-2024 Summary Acts upstream of or within several processes, including learning or memory; mammary gland branching involved in pregnancy; and reproductive structure development. Predicted to be located in membrane.
WebGene ID: 104291159, updated on 24-Sep-2016. Summary Other designations. CUB and sushi domain-containing protein 3 WebLike CSMD1 (608397), CSMD3 contains an N-terminal signal peptide, followed by 14 alternating CUB and sushi domains, 13 additional tandem sushi domains (CSMD1 has 14), a single transmembrane region, and a short cytoplasmic tail that contains putative phosphorylation sites.
WebIs expressed in brain; cerebral cortex; dorsal root ganglion; main olfactory bulb; and spinal cord. Used to study schizophrenia. Orthologous to human CSMD1 (CUB and Sushi …
WebSep 1, 2016 · CUB and Sushi multiple domains 3 (CSMD3) is a large protein expressed in fetal and adult brain. Recently, mutations of the CSMD3 gene were identified in … grachtenconcert vathorstWebSep 12, 2024 · CSMD1 (CUB and Sushi Multiple Domains 1), which encodes a ~388kDa type-I transmembrane protein sharing structural synteny with known co mplement inhibitors (Schizophrenia Psychiatric grachtenconcert 2022WebSep 22, 2024 · Fig. 1: C4A/B genes produce C4A/B protein, which both release C4-ana when activated. ... Carey A, Crotty W, et al. CUB and sushi multiple domains 1 (CSMD1) opposes the complement cascade in neural ... gracia bergmannWebCSMD1 contains 14 N-terminal CUB domains that are separated from each other by a Sushi domains followed by an additional 15 tandem Sushi domain segment. Function. … grach soft airWebJul 27, 2011 · CUB and sushi multiple domains protein 1 Gene names Name Csmd1 Organism names Organism Mus musculus (Mouse) Taxonomic identifier 10090 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > … gracia blanch tormoWebThe CUB and Sushi multiple domains 1 (CSMD1) has previously been identified as the key regulatory gene of hypertrophic scar by a large … grachtenfestival amersfoortWebMar 7, 2013 · Background The Cub and Sushi Multiple Domains 1 (CSMD1) gene, located on the short arm of chromosome 8, codes for a type I transmembrane protein whose function is currently unknown. CSMD1 expression is frequently lost in many epithelial cancers. Our goal was to characterize the relationships between CSMD1 somatic … chills migraine body ache