WebConstruction of Human Immune and Naive scFv Libraries Antibody phage display is the most commonly used in vitro selection technology for the generation of human recombinant antibodies and has yielded thousands of useful antibodies for … WebJan 1, 2012 · Naive libraries are constructed from rearranged V genes from B cells (IgM) of nonimmunized donors. Example for this library type is the naive human Fab library constructed by de Haard et al. ( 44 ), the scFv gene libraries HAL4/7/8 ( 25) and the McCafferty scFv library ( 45 ).
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